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Abalam (Abacavir)

Abalam is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), lamivudine (Epivir), emtricitabine (Emtriva), and stavudine (Zerit). During infection with HIV, the HIV virus multiplies within the body's cells. The newly-formed viruses then are released from the cells and spread throughout the body where they infect other cells. In this manner, the infection continually spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated. When producing new viruses, the HIV virus must manufacture new DNA for each virus. Reverse transcriptase is the enzyme that the virus uses to form this new DNA. Specifically, Abalam is converted within the body to its active form (carbovir triphosphate). This active form is similar to a compound (deoxyguanosine triphosphate), a chemical that is required by the HIV virus to make new DNA. The reverse transcriptase uses carbovir triphosphate instead of deoxyguanosine triphosphate for making DNA, and it is the carbovir triphosphate that interferes with the reverse transcriptase. Abalam does not kill existing HIV virus, and it is not a cure for HIV. The FDA approved Abalam in December 1998.

Other names for this medication:
Abacavir, Abalam, Epzicom, Kivexa, Abamune, Virol, Ziagen,

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Abalam is used together with other medicines to treat human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immunodeficiency syndrome (AIDS).

Abalam will not cure or prevent HIV infection or the symptoms of AIDS. It helps keep the HIV virus from reproducing, and appears to slow the destruction of the immune system. This may help delay the development of serious health problems that are usually related to AIDS or HIV infection. Abalam will not keep you from spreading HIV to other people. People who receive this medicine may continue to have other problems related to AIDS or HIV infection.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet
  • Solution

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A case of increased warfarin requirements during treatment with sofosbuvir and ribavirin for chronic hepatitis C virus (HCV) infection is reported. In the AMI group, 5 were complicated with ventricular septal perforation (VSP) and the remaining 11 were not (non-VSP). This study evaluated the present bypass selection strategy based on balloon test occlusion (BTO) in terms of clinical wymox tablets for kids and hemodynamic outcomes. Clinically relevant HO was associated with significant morbidity.

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