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Landel (Efonidipine)

Landel (0.01 or 0.03 mg/kg) decreased both blood pressure and heart rate, whereas nifedipine (0.003 mg/kg) decreased blood pressure and increased heart rate. Landel increased PO2, and the effect was more pronounced in the endocardial region than in the epicardial region.

Other names for this medication:
Efonidipine, Landel,

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During an active weight loss period low-carbohydrate diets more favorably affect triglyceride and HDL and less favorably affect LDL cholesterol concentrations. Human monitoring seems to be biased by a tendency towards sampling by means of horizontal transitions at the cost of diagonal transitions. The expected heterozygosity and Shannon-Wiener diversity index ranged from 0.022 to 0.879 and from 0.059 to 2.313, respectively. Use of enzymatic and cellular models producing free radicals: study of scavenging properties of manganese complexes with ESR spectroscopy.

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Data evaluating the complications of pulmonary vein isolation (PVI) using second-generation cryoballoons (CB) related to different anticoagulation regimes are limited. Consequently, Tn5 induced auxotrophic mutations could be equated with or distinguished from previously mapped mutations, and closely linked markers ordered, on the basis of marker recovery using the two classes of Hfr donor. This approach enables one to generate more accurate trees with a lower prediction error, meanwhile possibly avoiding overfitting. Fungal carbon is more enriched in 13C than photosynthates, allowing estimation of the proportion of carbon acquired heterotrophically from fungi in plant biomass. Two asparagine-linked glycosylation sites at positions 52 and 65 were found by comparing sequence data and peptide profiles of native and deglycosylated OIF fragments.

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The effects of prostaglandins, prostaglandin inhibitors, and oxygen on the closure of the ductus arteriosus, pulmonary arteries and umbilical vessels in vitro. Among smokers who planned to quit someday, the oldest were most likely to plan to quit within the next 3 months. Sumoylation regulates the transcriptional activity of different human NFAT isoforms in neurons. Exposure of Metarhizium acridum mycelium to light induces tolerance to UV-B radiation.

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Most TPVR-PVE patients were managed surgically as opposed to TAVR patients, and the mortality rate was high, especially in the TAVR cohort. Although the Sph element is similar in sequence to the SV40 element, the PLF Sph-binding factor is distinct from TEF-1, the factor that binds to the SV40 Sph motif. Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial. This year marks the tenth anniversary of the identification of the biological function of CRISPR-Cas as adaptive immune systems in bacteria.

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While different clinical presentations of EHK have been described, the distinctions have not been clear. Encapsulation in an alginate shell increased the time that cells could be maintained in three-dimensional culture for MCF-7 breast cancer cells prior to out-of-bead proliferation, permitting formation of spheroids over a period of 14 days without the need move the cell-laden beads to clean culture flasks to separate beads from underlying monolayers. It is concluded that digoxigenin DNA labelling and detection provides a simple, reliable, and efficient alternative to the use of biotin or radioactive isotopes for the detection of HPV DNA by in situ hybridisation. Changes in anterior pituitary hormone levels after serotonin 1A receptor stimulation.

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Marijuana has been used for a variety of medical purposes, including management of nausea and vomiting, appetite and immunologic stimulation in patients with HIV infection and AIDS, glaucoma, neurologic disorders, and pain relief. The aim of the Workshop was to provide a state-of-the-art review of imaging outcome measures for OA of the knee to help guide scientists and pharmaceutical companies who want to use MRI in multi-site studies of OA. To investigate morphological changes in vascular and circulating blood cells following exposure to detergent sclerosants sodium tetradecyl sulfate and polidocanol.

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Their sera were fractionated and the reaginic activity of the immunoglobulin classes was studied by passive cutaneous anaphylaxis testing in monkeys. Tarsal conjunctival swabs from patients of active trachoma were analyzed by direct immunofluorescence assay and polymerase chain reaction for Chlamydia trachomatis antigen. Seniors and health care providers focused mainly on antecedents and consequences of falling, whereas researchers described the fall event itself.

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Impact of Heterobasidion root-rot on fine root morphology and associated fungi in Picea abies stands on peat soils. Effects of ryanodine receptor activation on neurotransmitter release and neuronal cell death following kainic acid-induced status epilepticus.

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Treatment with doxycycline, topical corticosteroids and immunoadsorption led to rapid clinical remission. Our method has been successfully applied to the Urban Community of Bordeaux (France) on 4895 interventions related to flooding recorded during the 2009-2011 period. Colonic diverticular hemorrhage often recurs, and patients have high recurrence rates within short periods. Strategies combining primary care screening of 50- to 69-year-olds for proteinuria, diabetes, and hypertension followed by the routine use of ACE inhibitors, and optimal treatment of diabetes and hypertension, respectively, have the potential to reduce death and end-stage kidney disease and are likely to represent good value for money.

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Scores on the Power Mobility Screen and the CPCHILD were higher after intervention. Donor seropositivity and prednisolone therapy as risk factors for cytomegalovirus infection and disease in cyclosporin-treated renal allograft recipients. Solid-phase synthesis and biological activity of malformin C and its derivatives. Effect of water stress on physiological and growth charaters of Prunella vulgaris at the vegetative stage If GBC is confirmed, thin slice spiral CT can contribute valuable information on local spread.

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Data were collected from standardized medical records and the length of the cleft was checked on the pre-surgical dental cast for each child. In vivo phage display has been used extensively to screen for novel targets of tumor therapy.

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Nasal obstruction due to weakening of the nasal sidewall is a very common patient complaint. The level of Bcl-2 and Fas expression in thymoma tissue from patients with myasthenia gravis

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Mercury but not organochlorines inhibits muscarinic cholinergic receptor binding in the cerebrum of ringed seals (Phoca hispida). Our study indicates that the xeno-free culture system may be a good candidate for growth and expansion of hiPSCs as the stepping stone for stem cell research to further develop better and safer stem cells.

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The early diagnosis and treatment of malnutrition are therefore relevant components of oncological treatment. Predicting outcome of repeat milk, egg, or peanut oral food challenges.

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A review of the literature revealed only 94 well-documented cases of thymic carcinoma. Second, there might be a delay until one of the organisms reacts. This evidence supports the concept that clinical decision-making in the assessment of suspected acute coronary syndrome should be focused on obtaining the least amount of information that provides the highest benefit for informing the decisions of admission or discharge. Following these procedures, recovery and integrity of DNA, RNA, and protein by means of pulsed field electrophoresis, long-range PCR, real-time PCR, immunoblot, and immunohistochemistry (protocol I and II) as well as cell viability and steroidogenic capacity (protocol III) were investigated.

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This will allow improvement of the temporal resolution in UED experiments to well below 100 fs. Pneumonia leading to severe sepsis and critical illness including respiratory failure remains a common and therapeutically challenging diagnosis. Performing HTP can improve hopefulness and symptoms of patients, specially addicted ones. Ticarcillin/clavulanate appears to be an excellent replacement for initiating empiric therapy for these infections because of its safety and broad spectrum of activity, which includes gram-negative and -positive aerobic and anaerobic bacteria. The insertional inactivation of the recE gene renders cells very sensitive to DNA damaging agents and severely impairs intermolecular recombination, but does not markedly affect plasmid interstrand annealing and intramolecular recombination.

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Climate data, localisation of the sting, grade of anaphylaxis and therapy of hymenoptera stings. Meanwhile, lentiviral vector-mediated overexpression of miR-21 not only conferred resistance to 5-FU but also promoted proliferation, migration, and invasion of PATU8988 and PANC-1 cells.

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A screening method for the detection of the 35S promoter and the nopaline synthase terminator in genetically modified organisms in a real-time multiplex polymerase chain reaction using high-resolution melting-curve analysis. Prevalence of endocrine and metabolic disorders in subjects with erectile dysfunction: a comparative study. The nematode Caenorhabditis elegans is a widely adopted model organism for studying various neurobiological processes at the molecular and cellular level in vivo. Despite a normal SPECT result, a severe CACS identifies subjects at high long-term cardiac risk. Australia appears to contest theories suggesting a link between political economy and population health.

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Five isolants of Pseudomonas aeruginosa collected from clinical cases of equine genital infection and one standard strain of P. A case of sensorineural hearing loss involving a fibroepithelial polyp of the middle ear. From April 1995 through July 2004, 1,351 consecutive patients underwent brachytherapy for clinical stage T1b-T3a (American Joint Committee on Cancer, 2002) prostate cancer.

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Epidemiological and Clinical Characteristics of Kawasaki Disease and Factors Associated with Coronary Artery Abnormalities in East China: Nine Years Experience. This study found little empirical evidence to support the utility of DSM-5 severity rating scheme to differentiate adults with AN in terms of core eating disorder pathology or associated psychosocial impairment.

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Application of oscillation for efficiency improvement of continuous ethanol fermentation with Saccharomyces cerevisiae under very-high-gravity conditions. These errors can have an important clinical and socioeconomic impact. CT-Based Local Distribution Metric Improves Characterization of COPD. We followed the European League Against Rheumatism (EULAR) standardised procedures for guideline development. Patients were interviewed about oral health status, reason of dental visits and consumption of services, perceived need for care and self-care practices.

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CHIP-/- mice were found to phenocopy the motor deficiencies and some aspects of the hypogonadism observed in patients with STUB1 mutations. The bacteria-produced protein was similar in electrophoretic behavior to the 52- to 53-kilodalton protein synthesized in a cell-free translation system using rabbit reticulocyte lysate programmed with hybrid-selected hhcM-specific mRNA from Mahlavu hepatocellular carcinoma cells.

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Genetic overlap between autism, schizophrenia and bipolar disorder. We recently identified type II phosphatidylinositol 4-kinases alpha and beta (PI4KIIalpha and PI4KIIbeta) as being required for bacterial entry downstream of Met. Mesoporous silica/polymer composites utilizing intelligent caps onto mesopore walls toward practical low-dielectric materials.

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Indeed, distinct therapeutic approaches are required for each genotype. It is suggested that altered expression of the sop genes, which is due to relaxation of the mini-F plasmid DNA, causes both defective partitioning of the mini-F plasmids and increased IncG incompatibility in gyrB(HopA) mutants. Rapid dissociated Fe(III)-ascorbic acid complexes are formed after the mixing of Fe(II) (100 mkM) with ascorbic acid (1 mM) at pH-7,4.

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Replacement of the N alpha-blocking group in the formyl-methionyl tripeptide chemoattractant: an insight into the mode of binding at the receptor on rabbit neutrophils. No patient has developed locoregional recurrence to date or to the time of patient death. Safety and efficacy of quadrapeutics versus chemoradiation in head and neck carcinoma xenograft model.

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Molecular modelling suggested that terpenes with structures suitable for alignment within lipid lamellae were the most potent enhancers. CRP may be useful for distinguishing bacterial from RSV-associated pneumonia, although its role in discriminating against other respiratory viral-associated pneumonia needs further study.

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Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers. We analyzed 37 humic fractions with respect to their isotopic composition, structural characteristics, and properties responsible for stimulating plant root parameters.

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Contraceptive practices among married women of reproductive age in Bangladesh: a review of the evidence. We recorded data related to neonatal-perinatal characteristics, whole body cooling and outcome. Levels of SCFAs, lactate and PGE(2) in rectal dialysates could not explain the fermentation-associated hypersensitivity. The functional and morphologic changes were studied chronologically (from 10 to 40 wk) in mouse kidneys after injection with an actinium-225 (225Ac) nanogenerator, a molecular-sized, antibody-targeted, in vivo generator of alpha-particle-emitting elements. We have examined the cyto- and chemoarchitecture of the temporal and extended amygdala in the brain of a monotreme (the short-beaked echidna Tachyglossus aculeatus) using Nissl and myelin staining, enzyme histochemistry for acetylcholine esterase and NADPH diaphorase, immunohistochemistry for calcium binding proteins (parvalbumin, calbindin and calretinin) and tyrosine hydroxylase.

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parahaemolyticus has been a leading cause of foodborne outbreaks and bacterial infectious diarrhea since the 1990s, and most infections have been associated with the pandemic V. At the doses studied, cortisol-induced suppression of plasma interleukin-6 during and after cardiac surgery appears to be a saturable phenomenon at the concentration of plasma cortisol that is normally achieved after surgery in untreated patients. Limited additional release of cardiac troponin I and T in isoproterenol-treated beagle dogs with cardiac injury. Femur homograft derived from living donors is a valuable material for grafting jaw: it is safer, cheap, and available in programmed amounts and avoids a second operation field.

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Infection can promote the expression of human endogenous retroviruses by molecular mimicry or by functional mimicry. Charge contrast imaging (CCI) is a dynamic phenomenon recently reported in insulating and semiconducting materials imaged with low vacuum or variable pressure scanning electron microscopes (SEM). To evaluate whether clinical anxiety in children presenting to a pediatric pain management center is associated with a poorer treatment response for those who completed pain-focused cognitive behavioral therapy (CBT). Our objective was to analyze temporal trends in medication use and in-hospital mortality of AMI patients in a Chinese population. The recent advances in the diagnosis and treatment of patients with CVST have significantly lowered the associated mortality and morbidity and have improved the outcome of these patients.

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The possibility of multiple common allergenic determinants in mammalian sera is discussed. Phenothiazines, which undergo significant geometric relaxation upon oxidation, are used as fused-ring models to showcase that electron-donating methyl groups, which would generally be expected to lower oxidation potential, can lead to increased oxidation potentials when used as the steric drivers. The objective of the current study was to determine the relationship between serum vitamin D levels and the severity of atopic dermatitis (AD) in a Brazilian population.

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Atherogenesis is dependent upon monocyte influx into the vessel wall. Stress recovery index for risk stratification of asymptomatic patients following coronary bypass surgery. Homes remain the major place where children may be exposed to SHS. This study estimated the cost-effectiveness,from the Dutch health care perspective, of screening for albuminuria in the general Dutch population to prevent cardiovascular events (CVEs) with subsequent angiotensin-converting enzyme inhibitor treatment, using data from the Prevention of REnal and Vascular ENdstage Disease Intervention Trial (PREVEND IT).

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Neuronal population coding of perceived and memorized visual features in the lateral prefrontal cortex. Temperature and pH effects on the kinetic properties of some mitochondrial respiratory activities. Work-related rotator cuff injuries are a common cause of disability and employee time loss. Ochratoxin A (OTA), a mycotoxin and widespread food contaminant, is known for its patent nephrotoxicity and potential neurotoxicity.

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Adolescents with pituitary adenoma who do not receive postoperative radiation should be followed up closely and undergo imaging at more frequent intervals than do adult patients. A high incidence of WT1 abnormality in bilateral Wilms tumours in Japan, and the penetrance rates in children with WT1 germline mutation.

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Development and validation of a reliable and rapid LC-MS/MS method for simultaneous quantification of sacubitril and valsartan in rat plasma and its application to a pharmacokinetic study. Overall, males had a higher prevalence rate of substance abuse than females.

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The recombinant protein was released into the culture medium and, like the native protein, migrated as a double band at 45 and 47 kDa in sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis (PAGE) gels. The clinical data have been reviewed to determine whether the program is beneficial in supporting clients with their health maintenance goals, thus reducing occurrences of relapse, hospital readmission, and crisis or emergency room visits.

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Recent trials have facilitated the inclusion of HIV-infected patients in clinical trials, but the population is remains underrepresented in oncology trials. Causes and clinical manifestations of HIVAC depend on the degree of host immunosuppression. Geocoding was used to calculate driving time between CHIS households and nearby summer meals sites. Knowledge and acceptance of vasectomy is significantly better in males than female Nigerians living in Lagos.

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The lasers used were an glipizide or glyburide effects on pancreas argon-dye laser at 628 and 655 nm and a gold vapor laser at 628 nm. Genetic and metabolic engineering approaches for the production and delivery of L-asparaginases: An overview. Among early-stage ovarian cancer patients, practice patterns are widely divergent.

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Clinical and biological findings in 1,340 syphilitics (primo-secondary syphilis) having followed regular arseno-bismuth and bismuth therapy for at least 4 years Object Recognition in Flight: How Do Bees Distinguish between 3D Shapes? Potassium current activated by intracellular sodium in quail trigeminal ganglion neurons. difference between omeprazole and omeprazole delayed release To investigate whether long-term protection from light exposure affects the rate of disease progression in patients with autosomal recessive Stargardt disease (STGD1), measured using fundus autofluorescence imaging.

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Gene promoter methylation is a common finding in t-MDS/AML and has been associated to a coreg carvedilol 6 25 mg side effects shorter latency period from the treatment of the primary tumor. Expression of GABA(B) receptor in the avian auditory brainstem: ontogeny, afferent deprivation, and ultrastructure. Since the effusion was resistant to conservative therapy, we performed clipping of the thoracic duct under the diaphragm. In the third patient paraneoplastic polyarthritis had been diagnosed 5 months before a hypopharyngeal carcinoma was diagnosed. The virus was recovered from the respiratory tract of the patients and was transmitted to ferrets by the intranasal route.

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Histologic tracheal lesions were deciliation, mucous gland distortion, inflammatory cell infiltration, and squamous metaplasia. Reoperation was defined as the need for any surgical intervention to relieve bothersome LUTS after HoLEP. EBLM, by evaluating the role of diagnostic investigations in the clinical decision-making process, can help in translating the results of good quality research into everyday practice. After 9 months, odel uk national lottery all rats received sub-serosal gastric injections of horseradish peroxidase (HRP) during laparotomy.

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On the other hand, the substrate specificity of Ehrlich alpha-galactosidase appears to be quite narrow. We sought to identify affordable and sustainable methods to strengthen trauma care capabilities globally, especially in developing countries, using the Guidelines for Essential Trauma Care. The identification of small molecules that can induce new neurons from NSCs could facilitate jantoven tablet color regenerative medicine and drug development for neurodegenerative diseases. In addition, HCV infection affects adversely survival among patients with end-stage kidney disease. Frequency of parosteal ossification in paralysis due to transverse cord lesions

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Based on Southern blot analyses extended concatemeres of the HBx cDNA plasmid constituted a main part of the cointegrants. The proposed method enables entire molecules to be mutated from a noninteracting (ideal) state in an efficient and robust way, thus providing a means by which accurate absolute free energies of structurally complex molecules can be determined. FreeStyle systems use coulometry technology where the glucose signal is calculated from the total charge generated as a result of the glucose reaction in the sample. Prevalence of human rotavirus serotypes in some European countries 1981-1988. Cholera toxin discriminates between T helper 1 azelastine hydrochlorideside effects and 2 cells in T cell receptor-mediated activation: role of cAMP in T cell proliferation.