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Lexfin (Celecoxib)

From the result of this study, we could learn that Lexfin could reduce HFS that was induced by capecitabine. We used a systematic chemical approach to modify the structures of Lexfin and rofecoxib to produce a series of compounds that were tested for their effects on the viability of human prostate cancer PC-3 cells and their ability to induce apoptosis in these cells.

Other names for this medication:
Celecoxib, Celebrex, Artilog, Artose, Caditar, Celcox, Celcoxx, Celebra, Celeco, Celemax, Ciox, Colcibra, Coxib, Dilox, Dorex, Dorit, Flaxel, Impedil, Lexfin, Onsenal, Sionara, Solexa, Zycel,

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Lexfin comes as a capsule to take by mouth. It is usually taken once or twice a day. If you are taking up to 200 mg of Lexfin at a time, you may take the medication with or without food. If you are taking more than 200 mg of Lexfin at a time, you should take the medication with food. Ask your doctor or pharmacist if you are not sure if you need to take your medication with food. To help you remember to take Lexfin, take it around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Lexfin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you cannot swallow the capsules or if you are giving this medication to a child, you may open the capsules and sprinkle the contents over a teaspoon of cold or room temperature applesauce. You may prepare the mixture in advance and store it for up to 6 hours in a refrigerator. When you are ready to take your medication, swallow all of the mixture. Then drink water to wash down the mixture and be sure that you have swallowed all of it.

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Numerous studies show that many chronic pain populations show specific neuroplastic changes in the peripheral and central nervous system. Growth of new blood vessels in patients with neovascular AMD is driven by a complex process that involves a signal protein called vascular endothelial growth factor A (VEGF-A). Determination of oxLDL with the Mercodia method lead to lower results and detected only the changes with simvastatin. This opinion paper contends that a wide gap exists between the theory and practice of preventive dentistry. The patient may be advised to sit down during micturition, especially at night, but treatment is otherwise not necessary.

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FURTHER STUDIES ON NEW METHODS IN THE PHYSIOLOGY AND PATHOLOGY OF PLANTS. We studied temporal trends in admission BP and preadmission antihypertensive therapy from 2004 to 2010. Structure-property relationships: asymmetric alkylphenyl-substituted anthracene molecules for use in small-molecule solar cells.

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Here, we investigated the role of deltaPKC in ethanol-induced cardioprotection using a selective deltaPKC activator (psideltaRACK), or inhibitor (deltaV1-1), and a selective epsilonPKC inhibitor (epsilonV1-2) in isolated mouse hearts. The epidemiology differed significantly from that reported for F. Intracellular messengers, including cyclic nucleotides, appear to modulate the transport activity, apparently by activating specific protein kinases.

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Thirty men, 1-to-3-years post-RP, who took part in an ER program, participated in one of four focus groups. When considering currently available technologies, there are several unmet needs to be addressed. In healthy pigs, BM 13.177 decreased cardiac index and oxygen delivery and increased the pulmonary vascular resistance index. A new, high-sensitivity assay for cardiac troponin I (hs-cTnI) permits evaluation of the prognostic value of cardiac troponins within the reference interval.

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Regrettably, there currently is no reliable method of radiologically monitoring the propagation of RF lesions in real time. The role of Ese-2, an Ets family transcription factor, in gene regulation is not known. Herpes simplex virus type 2-transformed hamster embryo fibroblasts (333-8-9 cells) produce increased plasminogen activator (PA) compared with normal hamster cells. CHARACTERISTICS AND FACTORS INFLUENCING UNPROTECTED ANAL INTERCOURSE AMONG MEN WHO HAVE SEX WITH MEN IN FUYANG, CHINA. Data was collected through acute toxicity evaluations, motor behavior tests, necropsies, determination of neuronal survival by immunohistochemistry, Raman spectroscopic analysis of brain tissue, and HPLC measurement of dopamine in substantia nigra and striatum tissue.

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Sensitivity and directionality of these three sensors were measured in a tank, whilst the direction estimation capabilities of the accelerometers paired with the hydrophone, forming a vector sensor, were evaluated on a Medusa Class AUV, which was sailing around a deployed sound source. Elevated bacterial metabolism on the surface of marine sediments might limit the oxygen penetration into sediment, and such an environment might affect the genomes of bacteria isolated from these habitats. Structural and metabolic characteristics of erythrocytes in patients with systemic vasculitis To examine the views of primary care patients with OA knee towards exercise, explore factors that determine the acceptability and motivation to exercise, and to identify barriers that limit its use.

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Data from the original index open operation were collected retrospectively by review of the case notes. The effect of 1-nor-epinephrine upon the corpuscular volume and hematocrit. Direct link between glutathione oxidation and copper compartmentalization allows for rapid metabolic adjustments essential for normal neuronal function. Results of single and multiple injection schedules for the treatment of early syphilis with procaine penicillin in oil and aluminum monostearate. Systemic injection of IL-1 alpha or IL-1 beta (58.8 pmol at 1300 and 1500 h) failed to influence the afternoon LH surge seen in saline-injected control rats.

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Since the salivary glands in Periplaneta are innervated by dopaminergic and serotonergic neurons, PeaEbony probably also biochemically modifies dopamine and serotonin in these acinar glands. A cohort of all 235 neonates with cerebral palsy from a single Australian tertiary care center born between 1986 and 2003. All 10 lineages split before or during the fragmentation of the supercontinent Pangea in the Jurassic.

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The latest development together with measured data will be discussed in this article. Routine drainage of the thyroidectomy bed is not effective in decreasing the rate of postoperative complications after thyroid surgery, and it causes a prolonged hospital stay and surgical site infection. Response of rabbit testicular capsular contractions to testosterone, prostaglandin E1, and isoproterenol in vitro and in vivo. 2D and colour Doppler ultrasonography are used to diagnose the condition antenatally. All of the participants were evaluated using both disease-targeted mini-OQOL and QUALEFFO, generic instrument (EUROQoL), disability scale (Roland Morris Disability questionnaire- RMDQ) and chronic pain grade questionnaire.

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Further increase of the field strength may close the HOMO-LUMO gap of the dimer due to Stark shifts, accompanied by the emergence of a net magnetic moment from two nonmagnetic building blocks. Bioaccumulation of arsenic and silver by the caddisfly larvae Hydropsyche siltalai and H. Physiological genetics of melanotic tumours in Drosophila melanogaster. Further research is warranted into the short-term use of parecoxib in hospitalized patients with intractable malignant bone pain. Further insight into the differences between polarization-based image measurements and encoding of glucose information was provided through the use of principal component analysis (PCA).

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Activation of symport did not need the presence of specific inductor molecules in the medium. The standard model of particle physics is our best description yet of fundamental particles and their interactions, but it is known to be incomplete.

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During surgery, SF, menisci and condyles were retrieved and examined microscopically. Synthesis, spectral characterisation of 2-(5-methyl-1H-benzimidazol-2-yl)-4-bromo/nitro-phenols and their complexes with zinc(II) ion, and solvent effect on complexation. The physiological implications of these in vitro differences for larvae were studied in short-term in vivo and long-term exposure experiments.

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Detailed reconstruction of the musculature in Limnognathia maerski (Micrognathozoa) and comparison with other Gnathifera. The microbiota living in the human body has critical impacts on our health and disease, but a systems understanding of its relationships with disease remains limited. We have developed a model that can take advantage of the multiple genetic resources available for the mouse to study the mechanisms of in-stent restenosis. The sera of patients in remission, those of healthy unaffected relatives and normal controls contained only the IgG1 subclass. They demonstrate a variety of difficulties with which they must cope as they continue to survive.

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Suicidality and aggression during antidepressant treatment: authors misinterpreted earlier paper from the FDA. Experiments are described which show that the rabbit papilloma virus elicits an antibody of one type only, this being capable both of neutralizing the virus and of fixing complement in mixture with it. The photodegradation products, which were separated and characterized, show a moderate lytic and photolytic activity. Water shortage is a deleterious consequence of both population growth and climate change and is one of the most severe factors limiting global crop productivity. Osseointegrated dental implants in private practice: a long-term case series study.

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The subcellular distribution of 14C-glibenclamide in different tissues of rat. The effects of the selective 5-HT1A receptor agonist gepirone (10 and 20 mg orally) on neuroendocrine function and temperature were assessed using a single-blind cross-over design in 12 healthy male volunteers. The Chilean version of KIDSCREEN-27 instrument has adequate reliability and validity. Both were treated conservatively, the 2-year-old boy needed endotracheal intubation and mechanical ventilation. The clinical role of granisetron (Kytril) in the prevention of chemotherapy-induced emesis.

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Although a lack of standardized methodology makes cross-study comparisons challenging, trends and biases arise from this synthesis including a substantial focus on vertebrates, larvae or juveniles, the reef ecosystem, and chemosensory perception. One hospital was identified to be an overall outlier (higher SSIRs for three of the four procedures performed in its facilities), whereas two hospitals were outliers for one specific procedure throughout the entire study period. Although primary care physicians provide traditional diagnosis, treatment, and follow-up to patients with sexually transmitted diseases, their role in prevention efforts is becoming increasingly important. The absence of hypertension in obese hydralazine did not result in attenuation of cardioacceleration, cardiac hypertrophy, or intravascular volumes. The expression of receptors on human immunoregulating cells has been suppressed by the addition of staphylotoxin at a toxic concentration into the system.

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The psychophysiological basis of the compensatory development of visual perception in vision disorders Synthesis of diphtheria tox-gene products in Escherichia coli extracts. Purpose of this study was to determine how the human neutrophil elastase affects the interleukin-10 (IL-10) response in peripheral blood mononuclear cells (PBMC). Because of sudden abdominal pain accompanied by a fall in the hemoglobin level, the patient underwent an urgent laparotomy. A loss of beta-catenin induced by Dickkopf-1 can enhance MSCs differentiation into epithelial cells.

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Bedside flexible endoscopy was performed in this series not only to define the area and etiology of urethral obstruction, but also to facilitate catheter placement. As a model system, immobilization of acetylcholinesterase (AChE) was investigated using biomagnetic glasses composed of a magnetic core with a size tunable porous silica shell.

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Comparisons were made by calculating the sensitivities, specificities, and predictive values. The study aim was to analyze the mid-term prognosis of infective endocarditis (IE) in patients managed with medical therapy during the in-hospital phase and who had a good initial outcome.

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Following standard protocols, surveillance sometimes continues after apparent disease elimination. Erectile dysfunction patients may have characteristics of several disorders, in which case combined drug therapies may be more useful. Daily cost of delay to adequate antibiotic treatment among patients surviving a hospitalization with community-onset Acinetobacter baumannii pneumonia or sepsis. It is not known why there are aggregates or inclusions in affected tissues in mice with such mutations and in most forms of human motor neuron disease.

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In this study, we investigated the association between a region within the displacement loop (D-loop) in mtDNA that is highly susceptible to ROS and oxidative stress markers in chronic dialysis patients. We found that the CPG could induce respiratory related heart rate modulation that closely mimicked RSA. Three-dimensional map of the dimeric membrane domain of the human erythrocyte anion exchanger, Band 3. BBR selectively inhibits cellular proliferation and blocks E2- and P4-induced cell proliferation in UtLM but not in normal UtSMC cells.

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A further evaluation of the morphology of astrocyte in brain slices (ex vivo) and in vitro using an antibody against the astrocyte-specific cytoskeletal protein glial fibrillary acidic protein (GFAP) revealed that HAB astrocytes extended less processes than NAB cells. Mature DC loaded with HBsAg or HBcAg showed a greater capacity for autologous T-cell proliferation and antigen-specific IFN-gamma production than immature DC.

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Other data in favour of this hypothesis are the disappearance of the lesions after avoiding the mechanical trauma, the fact that there were other affected people at work, and that this factor has also been identified in the majority of cases reported previously. Furthermore, mutation of D666 and S1788 to cysteine resulted in disulfide bond formation across the A2-A3 interface, confirming the close proximity of D666 and S1787, and this covalent attachment of the A2 subunit significantly increased FVIIIa stability. Comment on Long-term effects of bariatric surgery on patients with obesity and chromosome 19.11-2 microdeletion. These models exhibited renal specific activation of the hypoxia inducible factor pathway (a VHL target). Enlightenment of occupational medicine teaching for undergraduate in American and European countries

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This review will summarize the progress of those studies on NGX6 and elucidate the potential application of NGX6 for some malignant diseases. Our results for the melting points for ice and letovicite are in good agreement with other experimental work. A spreading front that consists of membrane lobes and a single lipid bilayer was observed on the patterned silicon substrates by utilizing fluorescence interference contrast (FLIC) microscopy. Arthritis is the most common cause of disability, limiting the activities of adults throughout the world.

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Approaches to professional behaviour assessment: tools in the professionalism toolbox. Computed tomography (CT) revealed pancreatic head injury, and endoscopic retrograde pancreatography showed pancreatic duct disruption at the injury site along with contrast media leakage. In subacutely affected sheep, depression, inappetance, teeth grinding, tachycardia, weak ruminal movements and recumbency were noticed. dsRNA targeted to nonstructural genes (protease, polymerase, and helicase) effectively inhibited YHV replication.

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Estimates of the hazard ratio (HR) for IHD and stroke with smoking as an independent risk factor were obtained from the approximately 600,000 adult subjects in the Asia Pacific Cohort Studies Collaboration (APCSC). We expressed the carboxy-terminal portion of the E2 open reading frame (ORF)-encoded protein of human papillomavirus type 16 (HPV-16) and purified it to near homogeneity. Current FIGO staging classification for cancer of ovary, fallopian tube and peritoneum

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Vaccination with Replication Deficient Adenovectors Encoding YF-17D Antigens Induces Long-Lasting Protection from Severe Yellow Fever Virus Infection in Mice. To show the advantages of pedobarography as new diagnostic and rehabilitation method in prevention programs. We delineate benefits and limitations of these assays and highlight the key recent discoveries where live microscopy provided unprecedented insights into how cells defend themselves against genome-destabilizing effects of DNA damage. The results indicate the presence of a PT resistant alpha 2-adrenoceptor signal transduction mechanism. However, the simultaneous presence of 2 Bence Jones proteins of different immunologic types in the same patient is rare.

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Complex cell behaviors in development: recent progress and emerging challenges. We examined 83 patients with systemic lupus erythematosus (81 females and 2 males) aged between 19 and 71 years. Here, we propose a novel mechanism of balancing selection under temporally varying fitnesses. However, the mechanisms underlying the increased mortality associated with untimely treatment with Epo and the increased protection associated with timely treatment with Epo remain to be investigated. In theory, the use of antisense ODNs provides a method to specifically inhibit the intracellular expression of any disorder whose genetic aetiology is well known.

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We have explored the tissue localization of extracellular matrix metalloproteinases MMP-1 (fibroblast collagenase), MMP-2 (72-kDa gelatinase/Type IV collagenase), MMP-3 (stromelysin), MMP-8 (polymorphonuclear leukocyte collagenase) and MMP-9 (92-kDa gelatinase/Type IV collagenase) in the tissues around loose hip prostheses. The orbital injury ends with a foreign body (fragment of a pencil) in the orbit. Very careful anatomopathological examination of multiple sections of the tumour are necessary to distinguish it from benign tumours, especially myxomas.

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Our results reveal increased sensitivity to horizontal spatial frequency structure in personally familiar faces, further implicating the selective processing of this information in the face processing expertise exhibited by human observers throughout their daily lives. ULD patients had significantly more T2-weighted high-intensity signals on MRI than control subjects, due to the increased prevalence of these signals in the basal ganglia. Clinical aspects of invasive candidiasis in the surgical patient. The treatment of navicular fractures and pseudarthrose with electric and magnetic potentials Addition of pentoxifylline plus nifedipine to chemotherapy in patients with cisplatin-resistant cancers of the lung and other sites.

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TN lysed breast carcinoma and myeloma cell lines but did not lyse K562, which is sensitive to NK cells. Hyponatraemia is one of the most frequent disorders of the electrolyte metabolism. On an objective method for the study of the phenomenon of muscular defense

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However, in patients with high-risk stage II/III disease the time to progression is longer than that reported for similar patients treated with conventional systemic treatment. Management of vascular graft infections with soft tissue flap coverage: improving limb salvage rates--a veterans affairs experience. The health consequences of aerial spraying illicit crops: The case of Colombia. When erythrocytes from these mice were deoxygenated, greater than 90 percent of the cells displayed the same characteristic sickled shapes as erythrocytes from humans with sickle cell disease. Dietary carbohydrate intakes and in particular their food sources varied considerably between these 10 European countries.

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KR-31378 ameliorates atherosclerosis by blocking monocyte recruitment in hypercholestrolemic mice. Longitudinal analysis: TLE-HS presented progressive GM reduction in ipsilateral insula and occipital lobe, contralateral motor area, and bilateral temporal and frontal lobes. Prevention of hypoxemia: the simple, logical, but incorrect solution. However, both are still limited in their power to fully map antiviral resistance as cause of therapy failure.

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Correlation analysis carried out suggests that cortical plasticity is a complex dynamic system, the understanding of which requires not only the elucidation of the elementary cellular mechanisms forming it, but the study of the character of the interaction between them as well. Modeling in the quality by design environment: Regulatory requirements and recommendations for design space and control strategy appointment. However, there are limited data on the urine microbiology spectrum among patients with end-stage renal disease and on the development of antimicrobial resistance of uropathogens in these patients.

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We have been able to reliably genotype three classes of mutations in zebrafish, including point mutants, apc(hu745) (apc(mcr)), and p53(zy7) (p53(I166T)), a small deletion mutant (bap28(y75)) and oxactin common side effects a retroviral insertion mutant (wdr43(hi821a)). Fluoride varnishes are clinically effective but have not been shown to be superior to topical solutions or gels.(ABSTRACT TRUNCATED AT 250 WORDS)

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Hospitalization risk according to geriatric assessment and laboratory parameters in elderly hematologic cancer patients. Only cathodal cerebellar tDCS significantly reduced the amplitude of the N1, N2 and P3 components for both the target and novel stimuli. Pancreatic islets from SJL/J mice infected with the D variant of encephalomyocarditis virus (EMC-D virus) showed lymphocytic infiltration with moderate to severe destruction of beta cells. These observations together point to general and unique features of the chick pineal circadian system among animal clocks. Adopting rather conservative estimates for the minimal standard deviation on the pore and the skeleton size (0.2 and 0.04 microm, respectively), the presented calculations show that, if such a fixed lower limit on the size variance diclofenac sodium dosage for dogs exists, it will be impossible to decrease the A-term band broadening below a given critical value, no matter how small the domain size is made.

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Oral squamous cell carcinoma (OSCC) and cutaneous squamous cell carcinoma (CSCC) are epithelial neoplasms, of which OSCC has a worse prognosis. These observations are the first to implicate a regulatory role for cellular trafficking and benestan 10 mg xanax sorting in prestin function. Early stage primary ovarian mucinous carcinoma: Outcome-based clinicopathological study in comparison with serous carcinoma.

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The dielectric properties of living and dead unicellular action test vals positief lennik microorganisms (yeast) were studied in the microwave range, and the general regularities and differences were revealed. Hepatocytes are the major cell type populating the liver parenchyma and express several metabolic enzymes that are necessary for liver functions. In clinical practice it is also important to realize that mucosal changes usually persist for at least 8 weeks after the treatment of an acute infection. The concentration profiles are viewed as parabolas along the mesh lines parallel to x-axis or y-axis. IAEA Training Course Series TCS-37 Clinical Training of Medical Physicists Specializing in Radiation Oncology

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Our findings suggest that, among postgraduate physicians, CB and non-CB questions have similar effects on knowledge scores, but learners prefer CB questions. A distinct tadpole-shaped nanostructure characterized by ubat sporanox generic a spherical head and an extended shaft was identified in a single plasmid DNA (pDNA)-based polymeric micelle. Several SP proteins bound to sperm with a strong affinity to withstand these treatments. The number of ophthalmologists performing strabismus surgery on the pediatric population was analyzed, subdivided by high- and low-volume surgeons and career stage. The quantitative risk assessment included the following steps: (i) release of antimicrobial-resistant organisms from the farm, (ii) exposure of humans via consumption of contaminated beef products, and (iii) consequence of the antimicrobial-resistant infection.

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Hepatitis C virus (HCV) infection is a major public health issue. These parietal-premotor areas are principal candidates for abstract (effector-independent) movement encoding, promoting motor equivalence, and they form the highest level in the zolpidem tartrate 5 mg imageshack action representation hierarchy.

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The potential health risks of exposure to Radiofrequency Fields (RF) emitted by mobile phones are currently doxepin other drugs in same class as paxil of considerable public interest, such as the adverse effects on the circadian rhythmicities of biological systems. 201T1 SPECT was performed in 84 patients with suspected lung cancer. A dose-rate effect in the ultraviolet inactivation of bacterial spores.

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